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Vol. 15 No. 3 (2023): Carpathian Journal of Food Science and Technology

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Submitted
April 11, 2024
Published
December 10, 2025

Phytochemical profile of Agrimonia eupatoria L. from Bulgaria and effects of its extracts on Galleria mellonella (L.) (lepidoptera: pyralidae) larvae

Hülya Doğan
Yozgat Bozok University
Hatice Baş
Yozgat Bozok University
Hafize Fidan
University of Food Technologies, Plovdiv
Stanko Stankov
University of Food Technologies, Plovdiv
Albena Stoyanova
University of Food Technologies, Plovdiv
Tansu Uskutoğlu
Yozgat Bozok University
Belgin Coşge Şenkal
Yozgat Bozok University
Güngör Yılmaz
Yozgat Bozok University

Corresponding Author(s) : Hafize Fidan

hfidan@abv.bg

Carpathian Journal of Food Science and Technology, Vol. 15 No. 3 (2023): Carpathian Journal of Food Science and Technology

Abstract

Plants contain polyphenolic compounds such as phenolic acids, flavonoids, stilbenes, lignans, essential oils, etc., which are endowed with antioxidant properties. This study aimed to correlate the total phenolic compound and flavonoid content of Agrimonia eupatoria L. with its antioxidant properties and to determine some mineral elements (Na, K, Ca, Mg, P). The antioxidant capacity of the extract was tested by three methods (DPPH, FRAP, and TEAC). According to the results, the antioxidant content of A. eupatoria was found to be high (IC50=38.03±0.01μg/mL). Total phenolic and flavonoid contents were found as 13.66±0.38 mg GAE/g and 4.65±0.01mg QE/g, respectively. Besides, the major components found in A. eupatoria were α-pinene (62.72%), n-hexadecanoic acid (11.41%), (5E,9E)-farnesyl acetone (6.64%), and (5E,9Z)-farnesyl acetone (3.65%). Heavy metal content in A. eupatoria was found within WHO limits. It was also investigated whether A. eupatoria has toxic effects. Because a medicinal plant is not supposed to harm metabolism, for this investigation, larvae stage of Galleria mellonella had selected as a test organism. In order to investigate the toxic effects, oxidative stress parameters (SOD, CAT, GST, GPx, MDA) and AChE activity were measured. And no harmful effects were observed at the doses administered at 24, 48, and 72 h.

Keywords

Antioxidant activity Essential oil Mineral matter Oxidative stress
Doğan, H., Baş, H., Fidan, H., Stankov, S., Stoyanova, A., Uskutoğlu, T., Şenkal, B. C., & Yılmaz, G. (2025). Phytochemical profile of <i>Agrimonia eupatoria L.</i> from Bulgaria and effects of its extracts on <i>Galleria mellonella (L.) (lepidoptera: pyralidae)</i> larvae. Carpathian Journal of Food Science and Technology, 15(3), 58–69. Retrieved from https://opacj.org/carpathian-fst/article/view/10.34302_crpjfst_2023.15.3.5
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Author Biographies

Hülya Doğan, Yozgat Bozok University

Yozgat Vocational School

Hatice Baş, Yozgat Bozok University

Faculty of Science and Literature

Tansu Uskutoğlu, Yozgat Bozok University

Yozgat Vocational School

Belgin Coşge Şenkal, Yozgat Bozok University

Yozgat Vocational School

Güngör Yılmaz, Yozgat Bozok University

Yozgat Vocational School

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